Class Action Lawsuit Investigations – It was found that from the analysis of the large research and studies that erectile dysfunction drugs or medicines do not cause Melanoma (deadly type of Skin Cancer), it was found from the researchers that overall 11 percent increased risk of melanoma in the people who used drugs like Viagra or other erectile dysfunction medicines, but there was no evidence that these medicines cause melanoma. Shamis & Gentile, P.A. class action lawsuit investigations team looks into the relationship between cialis and Melanoma.
There was a study published in JAMA Internal medicine in 2014. It was found that the men who used Viagra (sildenafil) regularly were 84% more keen to develop melanoma in to themselves.
Phosphodiesterace type 5:
PDE5 inhibitors are the class of same drugs which include Cialis (tadalafil), Stendra (avanafil),and levitra (vardenafil) all having the same biochemistry, the researchers did not include these drugs in their studies.
Can PDE5 inhibitors cause Melanoma?
The American urological association and Europian association urology guidelines recommended PDE5 inhibitors for their patients with ED. The recent research has claimed that PDE5 can increase the melanoma risk. The PDE5 uses the same biological pathway as the melanoma cells do which some studies show that this could help the melanoma, a to spread rapidly. The drugs do not cause the melanoma but rather they give a pathway for melanoma to spread which makes melanoma to develop in to an individual.
PDE5 how it works?
PDE5 inhibitors increase the blood flow in to the vessels and helps them to open up and increases the volume of the blood flow in to the area, they accomplish this by releasing nitrous oxide in to the vessels having poor blood flow in them, which triggers simultaneously the enzyme known as guanylate cyclase it inturn also triggers another chemical which is the cyclic guanosine monophosphate (Cgmp).These drugs are also used to treat high blood pressure or hypertension as they relax the blood vessels, but the PDE5 inhibitors are not recommended if you intake nitrovasodilators for angina pectoris, as they cause drop in blood pressure.
Risks involved
It was found from the research and analysis of the data of the Harvard school of public health that 26000 men who intake Viagra between the year 2000 and 2010 of which 13.4 percent of those men developed some or the other form of skin cancer. They concluded that if you took Viagra regularly then you are more likely to develop melanoma, and if you discontinue the use of Viagra then you are less likely to get affected by melanoma. These tests or analysis were done when other factors, such as genetics, hair and skin color etc..were neglected.
Medical researchers insist more studies to be made in order to confirm that whether truly these drugs can cause this deadly skin cancer.
Types of Melanoma
- Acral Melanoma:
Also called as acral lentiginous melanoma, is a rare type of skin cancer which is common on palms, soles, under finger. If you are having darker skin you are more likely to have acral melanoma.
- Cutaneous melanoma:
Most common type of melanoma worldwide which is the melanoma of the skin. if you are more exposed to UV rays cutaneous melanoma is more likely to effect you.
- Uveal melanoma:
You can call it melanoma of eye. This type of melanoma is very rare, the cause of this type of melanoma is not yet been found yet, but it is believed that it is caused due to exposure of the sun. If you have this type of melanoma then you can experience flashes, floaters and also other similar kinds of eye defects.
- Mucosal melanoma:
This type of melanoma is not caused by exposure of the sun or other sources of UV radiation it is believed so. It just accounts for 1% of all melanoma diagnosis or treatment. It invades mucosal tissue in the body including the lining sinuses and mouth, nasal cavity, GI tract, Vagina, Anus and other mucosal areas.
- Other types:
Melanoma is deadliest type of skin cancer thamkfully it is not the most common disease.
BCC- Basal cell carcinoma
SCC- Squamous cell carcinoma
BCC and SCC make 99%of skin cancer treatment at United States.
“You can contact DermTech for Melanoma, Non melanoma and also other inflammatory skin disease”
Melanoma statistics
- About 7230 people in united states are expected to die of melanoma for the year 2019 in which 4740 are male and 2490 are female.
- About 96480 new patients will be treated for melanoma in the year 2019 in which 57220 are men and 39260 are women.
The rate of melanoma is rising rapidly over a dacade.
Conclusion
- More research and study has to be made to be sure that ED drugs do really cause melanoma.
- Early diagnosis of melanoma is important to decrease the danger of skin cancer.
- Melanoma type of skin cancer is rapidly increasing in united states.
- It is found from the research that biological patchway of the drugs causes the spread of melanoma and not the drugs.
To learn more about our Class Action Lawsuit Investigations and studies, contact us or visit our investigations page today!
